A weakened Manchester United were beaten 2-1 at home by Leicester City on Tuesday, ending Manchester City's wait to be crowned Premier League champions.
Manchester City and Arsenal closed in on Premier League leaders Liverpool with contrasting victories on Saturday as Manchester United's bubble was burst by Fulham.
Brazilian Casemiro struck late to send Manchester United into the FA Cup quarter-finals with a 1-0 victory over Nottingham Forest as teenagers Jayden Danns and Lewis Koumas inspired Liverpool to a 3-0 win over Southampton on Wednesday.
AC Milan grabbed a 1-1 draw at Manchester United in the blockbuster Europa League last-16 first-leg at Old Trafford on Thursday.
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IMAGES from the Premier League matches played on Saturday
United are 16th in the standings with a game in hand heading into the international break.
Images from the English Premier League matches played on Saturday.
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Brighton & Hove Albion scored three times in the second half to fight back from two goals down and beat Manchester City
Barcelona crashed out of the Champions League following a 3-0 defeat at Bayern Munich on Wednesday, failing to make it past the group stage of the competition for the first time since the 2000-01 season.